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Verified Commit 3ae59baf authored by Marta Girona Alarcon's avatar Marta Girona Alarcon Committed by GitLab UZH
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added 2 x csv tables

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Product number , Device , Reference , Company , State , Manufacturing country ,Comment
1,ECG ," BMA-200, NEE-3 ", CWE Inc. , Pennsylvania , USA ,
2,ECG ,BioAmp FE231, ADInstruments , Dunedin , New Zealand ,Ony used in ESRF_2021_November
3,Small animal ventilator - hutch, SAR-1000 , CWE Inc. , Pennsylvania , USA ,
4,Circulation thermostat pump , Haake L / SAHARA PPO S5P , Thermo Fisher Scientific Inc. , Schwerte , Germany ,
5, Flowmeter and gas mixer , EFM-4 , CWE Inc. , Pennsylvania , USA ,
6,"Data acquisition box, BNC-to-USB, used together with LabChart ", 8/35 Series , ADInstruments , Dunedin , New Zealand ,Ony used in ESRF_2021_November
7,"Data acquisition box, BNC-to-USB, used together with LabVIEW", DT9804 , Measurement Computing Corp. , Massachusetts , USA ,
8,Tracheal cannula for mouse - metal , 73-2731 - OD 1.0 mm L 13 mm , Hugo Sachs Elektronik , March-Hugstetten , Germany ,
9,Stereotaxic U-frame ," SGL M digital 68801, 68665, 68202, 68207 ", RWD Life Science Co. , Shenzen , China ,
10, Lateral ventricle fitting tube (#1) 0.69 mm ID x 1.14 mm OD , C312VT vinyl - P1-8F027X045P01 , Bilaney Consultants GmbH , Duesseldorf , Germany ,Only used in ESRF
11," Lateral ventricle fitting tube (#2) 0.23"" ID x 0.38"" OD ", P50 Tygon , Access Technologies , Illinois , USA ,
12, Compression fitting 1 mm , HA-55750-01 , BGB Analytik AG , Heidelberg , Germany ,
13, 25 uL Hamilton syringe without needle , HA-80230 , BGB Analytik AG , Heidelberg , Germany ,
14,Single syringe I/W nanoliter pump , KDS Legato 130 , KD Scientific Inc , Holliston , USA ,
15, MRI microcannula ," 328OP/PK/Spc 2.2, 2.3 or 2.5 mm ", Bilaney Consultants GmbH , Duesseldorf , Germany ,
16, Dental drill , OmniDrill35 , World Precision Instruments GmbH , Friedberg , Germany ,
17, Health monitoring device PhysioSuite ," PS-03,CBL-ANAOUT-MINI, E-RT-0002, E-RT-2-CUS, PS-05-module ", Kent Scientific Corp. , Torrington , USA ,
18,Microcontroller board,Arduino Mega 2560,Arduino,Ivrea,Italy,Ony used in ESRF
19," ESRF, CLS camera ", pco.edge 5.5 , PCO AG , Kelheim , Germany ,
20, Spring-8 camera , Hamamatsu ORCA-Flash4.0 ,Hamamatsu Corp.,Bridgewater,"USA ",Only used in SPring-8
21, Insulin syringe , Omnican 50 ,"B.Braun Melsungen AG ",Melsungen,Germany,
22, Cisterna magna fitting tube , Polyethylene 50 /23G ,"UNO Life Solutions ","PC Zevenaar ","Netherlands ",Ony used in ESRF
23, Cisterna magna metal clip , 00398-02 , Fine Scientific Tools Inc , Heidelberg , Germany ,Ony used in ESRF
24, Tissue glue , VetBondTM 3M , 3M , Minnesota , USA ,
25, Anesthesia induction chamber , V100-V , RWD Life Science Co. , Shenzen , China ,
26, Reptile temperature controller , ITC-308 WIFI , Inkbird Tech. C.L , Shenzen , China ,
27, Contrast agent , ExiTronTM nano12000 , ViscoverTM nanoPET Pharma GmbH , Berlin , Germany ,
28, Monitoring software LabChart ,LabChart 8, ADInstruments , Dunedin , New Zealand ,Ony used in ESRF_2021_November
29, Monitoring software LabVIEW ,2022 Q3, National Instruments ,Austin,"USA ",
30, Wrap bandage - holder , KRUUSE Vet-Flex 5cm x 4.5m , Covetrus CH , Lyssach , Switzerland ,
31, Low-Profile Anesthesia mask Small , E-VETFLO-0801 , Kent Scientific Corp. , Torrington , USA ,
32, Superglue accelerator INSTA-SET, GTIN 707336151009 , Toni Clark GmbH , Luebbecke ,Germany,
33,Rodent warmer X1 with mouse heating pad - surgery," 50304, 53800M, 53810 ", Stoelting Co. , New York , USA ,
34,Grooming clipper Aesculap Exacta , GT416 , Groomers Mall GmbH , Ebmatingen , Switzerland ,
35,Small animal ventilator - surgery, MiniVent - Model 845 , Hugo Sachs Elektronik , March-Hugstetten , Germany ,Used also in hutch for ESRF_2021_November
36,Rotary saw,2050 Stylo+,Dremel - Robert Bosch Tool Corp.,Mount Prospect,"USA ",
37,"1 mL syringe ", Injekt Fluer Solo 9166017V ,"B.Braun Melsungen AG "," Melsungen ","Germany ",
38,"26 G needle "," Sterican 4670008S-01 ","B.Braun Melsungen AG "," Melsungen ","Germany ",
39,"22 G needle "," Sterican 4670032S-01 ","B.Braun Melsungen AG "," Melsungen ","Germany ",
40,"Lubricant eye ointment ",Blache Augensalbe Tb 5 g ,"Bausch +Lomb ", Vaughan Ontario ,"Canada ",
41,"Bonewax "," Ehicon REF W31 ","B.Braun Melsungen AG "," Melsungen ","Germany ",
42,"Surgical blade "," B.Braun ","Aesculap AG ","Tuttlingen ","Germany ",
43,"Vannas Spring Scissors ", Fine Science Tools 15000-00 ,"Fine Science Tools ","Foster City CA "," USA ",
44,"Spring Scissors - 8mm Cutting Edge ", Fine Science Tools 15025-10 ,"Fine Science Tools ","Foster City CA "," USA ",
45,"Acrylic glue Cyano "," Cyano fast, REF 152261 ","Hager Werken ","Duisburg "," Germany ",
46,"Surgical tape ","3M Transpore White Surgical Tape, 1534/1544 Series ","3M ","Minnesota ","USA ",
47,"Sugi sponge points ","43.100.603 ","Curaden Dentaldepot ","Dietikon ","Switzerland ",
48,"Sterile threaded needle ","Silkam, 6-0 DS12 45 cm, REF C0762067 ",B.Braun Melsungen AG ,"Melsungen ","Germany ",
49,"Non-absorbable braided silk suture ","Siyze 6/0, 18020-20 ","Fine Science Tools ",Foster City CA ," USA ",
50,"Microvascular clamps ","2 single clamps vessel size 0.6-1.5 mm, REF 00399 "," S&T AG ","Neuhausen ","Switzerland ",
51,"Saline solution ","0.9 % NaCl ","Fresenius Kabi AG ","Oberdorf ","Switzerland ",
52,"20 % Glucose ","2356746 ","B.Braun Melsungen AG ","Melsungen ","Germany ",
53,"Hair removal cream ","Veet ","Reckit Benckiser ",Slough,England,
54,"Hardened Fine Scissors ","14090-09 ","Fine Science Tools ","Foster City CA "," USA ",
55,"Extra Fine Graefe Forceps Straight ","11150-10 ","Fine Science Tools ","Foster City CA "," USA ",
56,"Extra Fine Graefe Forceps Curved ","11152-10 ","Fine Science Tools ",Foster City CA ," USA ",
57,"S&T Forceps - SuperGrip Tips ","00649-11 ","Fine Science Tools ",Foster City CA ," USA ",
58,"Tweezers 5-SA ","5SA ","Rubistech ","Stabio ","Switzerland ",
59,"Ball mill, carbide 0.5 mm ","115-6025 ","Circuit medic ","Haverhill, MA "," USA ",
60,"Ball mill, carbide 0.8 mm ","115-6001 ","Circuit medic ","Haverhill, MA "," USA ",
61,"Ball mill, carbide 1.0 mm ","115-6002 ","Cicuit medic ","Haverhill, MA "," USA ",
62,"Ball mill, carbide 1.2 mm ","115-6003 ","Circuit medic ","Haverhill, MA "," USA ",
63,"Non-woven swabs ","V0043-010 Nobatop 16 ","Nobamed Paul Danz AG ","Wetter (Ruhr) "," Germany ",
64,"Mathieu Needle Holders ","12010-14 ","Fine Science Tools ",Foster City CA ," USA ",
65,"Student Halsey Needle Holder ","91201-13 ","Fine Science Tools ",Foster City CA ," USA ",
66,"Fiberoptic Gooseneck light guide ","Photonic ","Photonic Optics ",Vienna,Austria,
67,"Light source PL 2000 ","596-20-250 ","Photonic Optics ",Vienna,Austria,
68,"Heating pad ","465265 ","ThermoLux ","Murrhardt ","Germany ",
69,"Cisterna magna Polyurethane tubing French 2 0.012 "" ID "," BC-2P ","UNO Life Solutions ","PC Zevenaar ","Netherlands ",Only used in ESRF
70,"Cotton applicator small head ","REF 1001230 Boettger ","Applimed SA ",Chatel-St-Denis ,Switzerland ,
......@@ -31,6 +31,8 @@ The list of used contrast agents is available under the Zenodo download entry "t
![](images/post_mortem_overview.png)
*Fig. 2. Ex vivo coronal slices of three different mice injected with (left) Gadolinium-based, (middle) Barium-based and (right) Gold-based contrast agent*
We considered the Barium-based contrast agent (CA) to be the most promissing one and therefore decided to employ it for the *in vivo* experiments.
### Experiment 2: CSF spaces segmentation
![](images/JP26-invivo-2scan-phase3-postinjection-brain-80-90min_web.png){width="600"}
......@@ -51,7 +53,16 @@ Three dimensional rendering of CSF spaces enclosed in the mouse skull: Infusion
## Additional materials
We have additively manufactured the mouse holder, optimized for vertical imaging while ensuring fixation of the mouse skull.
![](images/holder_1.jpeg)
*Fig. X. *
###
Equipment and consumables are provided as a table:
<table>
<tr>
<td> Product number </td>
......
Mouse number,Element,Molecular Weight,Injection Site,Contrast agent commercial name
21,Iodine,High MW,ventricle,ExiTron P
23,Gadolinium,High MW,ventricle,GadoSpin P
24,Gold,Nanoparticles,ventricle,Aurovist 15 nm
22,Gadolinium,Low MW,ventricle,Gadodiamide
19,Barium,Nanoparticles,ventricle,ExiTron nano 12000
30,Gold,Nanoparticles,cisterna magna,Aurovist 15 nm
25,Barium,Nanoparticles,cisterna magna,ExiTron nano 12000
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