@@ -18,3 +27,7 @@ The CNS fluid spaces and barriers are also of fundamental importance for CNS imm
We aim to establish a comprehensive understanding of CSF dynamics, associated transport processes, and corresponding CNS barriers in mouse models, and then analyze changes due to aging, neuroinflammation, and neurodegeneration. Our team consists of biologists, veterinarians, physicists, physiologists, neuroscientists, and engineers that bring together the required cross-disciplinary expertise. We will pursue our goals by a unique combination of technologies including new reporter mice, in vivo synchrotron radiation-based micro computed tomography (SRµCT), magnetic resonance imaging (MRI), near-infrared and two-photon fluorescence imaging of CSF pathways and CNS barriers, and computational modelling.
